Volume-6, Issue-9, September 2020

Abstract

The aerospace industry is developing lighter, stronger and more heat- and corrosion-resistant components to reduce manufacturing costs and fuel consumption. To achieve this goal, laser welding represents a real opportunity to replace the riveting assemblies developed in the 1920s. In this article, we present our research to obtain the weldability domain of AA6061 aluminium alloy by autogenous disk laser welding. A systematic study of the samples butt-welded by Xray and optical microscopy allowed us to determine the defects and the dimensions of the weld beads according to the process parameters. The data analysis with the CORICO software made it possible to determine the regression models considering the welding parameters in order to avoid the appearance of defects such as melt pool collapse, lack of penetration or hot cracking. A range of weldability was defined for power values between 2000 to 2500 W, welding speeds below 4m/min and focal diameters below 170 microns.

Keywords: aluminium alloy, laser welding, weldability domain.

References

Keywords: aluminium alloy, laser welding, weldability domain.

Abstract

Based on the Hamilton’s principle, invariants are proposed to describe the processes of formation and evolution of the structure of the metal interface under friction. These invariants can be used, among other things, in the creation, evolution and destruction of nanomaterials.

Keywords: nano, submicro, micro, meso and macro levels of deformation, equilibrium and non-equilibrium deformation, invariants.

References

Keywords: nano, submicro, micro, meso and macro levels of deformation, equilibrium and non-equilibrium deformation, invariants.

Abstract

Indian spices that provide flavor, color, and aroma to food also possess many therapeutic properties. Ancient Indian texts of Ayurveda, an Indian system of medicine, detailed the medicinal properties of these plants and their therapeutic usage. Recent scientific research has established the presence of many active compounds in these spices that are known to possess specific pharmacological properties. The therapeutic efficacy of these individual spices for specific pharmacological actions has also been established by experimental and clinical studies. The medicinal effects traditionally ascribed to Indian spices are validated by modern pharmacological and experimental techniques, thus providing a scientific rationale to their traditional therapeutic usage. Many plant-derived molecules have shown a promising effect in therapeutics. Among the plants investigated to date, one showing enormous potential is the Piperaceae. Piperine is an alkaloid found naturally in plants belonging to the pyridine group of Piperaceae family, such as Piper nigrum and Piper cubeba. It is widely used in various herbal cough syrups and it is also used in anti inflammatory, anti malarial, anti leukemia treatment. So the present study was aimed to extract the phytochemical compounds in different solvent system in Piper nigrum and Piper cubeba. In preliminary screening and confirmatory test it was identified as alkaloid. High antioxidant activity was found in Piper cubeba ethanol extract i.e. 77.61±0.02% in comparison to Piper nigrum extracts with 74.61±0.02% with IC50 values10.54±0.12µg/mg and 14.15±0.02 µg/mg respectively.

Keywords: Piper nigrum, Piper cubeba, Phytochemical, Antioxidant activity, DPPH.

References

Keywords: Piper nigrum, Piper cubeba, Phytochemical, Antioxidant activity, DPPH.

Abstract

The Microsponge Drug Delivery System (MDS) is a patented technology has been successively used for the controlled release of topical agents which consist of macro porous beads, typically 10-25 microns in a diameter, which are loaded with active agent. Allowing a sustained flow of substances out of the sphere, the outer surface is typically porous, This system can suspend or entrap a wide variety of substances, and incorporated into a formulated product such as a liquid, gel, cream, or powder. The Microsponge shows time mode release when applied to the skin and they also response to otherstimuli like rubbing, pH, etc. MDS technology is currently used in different dosage forms like cosmetics, over the counter (OTC) skin care, sunscreens and prescription products. Microsponge technology allows entrapment of ingredients and it also shows reduced side effects, more stability, increased elegance and enhanced formulation flexibility. In addition, various studies have showed that microsponge systems are non-irritating, non-mutagenic, non-allergenic, and non-toxic. Microspheres can be prepared by different methods using emulsion system or by suspension polymerization in liquid system.

Keywords: Microsponge, Porous-beads, controlled-release, Quisi-emulsion-solvent- diffusion method, Liquid-liquidsuspension-method.

References

Keywords: Microsponge, Porous-beads, controlled-release, Quisi-emulsion-solvent- diffusion method, Liquid-liquidsuspension-method.